Description
ZEISS Lightsheet 7 is a light sheet fluorescence imaging system designed for multiview imaging of living and optically cleared specimens.
The system combines fast volumetric acquisition with gentle plane illumination, enabling long-term observation of biological processes while preserving sample integrity.
With its flexible configuration and stable enclosed architecture, Lightsheet 7 supports a wide range of applications — from live-cell imaging to large cleared tissue and whole-organism studies.
Key Features
- Multiview imaging for complete 3D reconstruction of complex samples.
- Long-term imaging of living specimens with reduced phototoxicity.
- Imaging of large cleared samples up to 2 cm in size.
- Broad refractive index compatibility (1.33 – 1.58).
- High stability and reproducibility in long experiments.
Technologies
- Light sheet fluorescence system (LSFM): fast optical sectioning with minimal light exposure.
- Multiview imaging: improved image quality and reconstruction accuracy.
- Pivot Scan: artifact-free imaging with enhanced quality.
- Smart software tools: automated control and data processing.
Applications
- Imaging of optically cleared tissues and organs.
- Developmental biology and whole-organism studies.
- Long-term live imaging of cells and model organisms.
- Organoids, spheroids, and large biological samples.
- 3D visualization of complex biological systems.
Advantages
- System flexibility: adapts to different sample types and clearing methods.
- Large sample capability: imaging of millimeter-scale specimens.
- Gentle plane illumination: minimal photodamage for long-term imaging.
- High speed: fast volumetric acquisition using camera-based detection.
- Ease of use: turnkey system with automated workflows.
ZEISS Lightsheet 7 is a versatile imaging system for both living and cleared samples, delivering reliable 3D visualization across a wide range of biological applications.
